Shadfan, AdamDarwiche, HawraaBlanco, JesusGillenwater, AnnRichards-Kortum, RebeccaTkaczyk, Tomasz S.2017-03-072017-03-072017Shadfan, Adam, Darwiche, Hawraa, Blanco, Jesus, et al.. "Development of a multimodal foveated endomicroscope for the detection of oral cancer." <i>Biomedical Optics Express,</i> 8, no. 3 (2017) The Optical Society: 1525-1535. https://doi.org/10.1364/BOE.8.001525.https://hdl.handle.net/1911/94025A multimodal endomicroscope was developed for cancer detection that combines hyperspectral and confocal imaging through a single foveated objective and a vibrating optical fiber bundle. Standard clinical examination has a limited ability to identify early stage oral cancer. Optical detection methods are typically restricted by either achievable resolution or a small field-of-view. By combining high resolution and widefield spectral imaging into a single probe, a device was developed that provides spectral and spatial information over a 5 mm field to locate suspicious lesions that can then be inspected in high resolution mode. The device was evaluated on ex vivo biopsies of human oral tumors.engArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.Journal articlehttps://doi.org/10.1364/BOE.8.001525