2021-03-022021-03-022021-01-26Nicolaou, Kyriacos C. and Cai, Quan, "Total synthesis of trioxacarcin DC-45-A2 and preparation of trioxacarcin analogs." Patent US10899773B2. issued 2021-01-26. Retrieved from <a href="https://hdl.handle.net/1911/110129">https://hdl.handle.net/1911/110129</a>.https://hdl.handle.net/1911/110129"In one aspect, the present invention provides novel derivatives of trioxacarin analogs of the formula (I) wherein the variables are as defined herein. The application also provides compositions, methods of treatment, and methods of synthesis thereof. "76engUtility patentUS10899773B2