Poulose, Aby CheruvathoorVeeranarayanan, SrivaniMohamed, M. SheikhAburto, Rebeca RomeroMitcham, TrevorBouchard, Richard R.Ajayan, Pulickel M.Sakamoto, YasushiMaekawa, ToruKumar, D. Sakthi2016-12-012016-12-012016Poulose, Aby Cheruvathoor, Veeranarayanan, Srivani, Mohamed, M. Sheikh, et al.. "Multifunctional Cu2−xTe Nanocubes Mediated Combination Therapy for Multi-Drug Resistant MDA MB 453." <i>Scientific Reports,</i> 6, (2016) Springer Nature: http://dx.doi.org/10.1038/srep35961.https://hdl.handle.net/1911/92737Hypermethylated cancer populations are hard to treat due to their enhanced chemo-resistance, characterized by aberrant methylated DNA subunits. Herein, we report on invoking response from such a cancer lineage to chemotherapy utilizing multifunctional copper telluride (Cu2−XTe) nanocubes (NCs) as photothermal and photodynamic agents, leading to significant anticancer activity. The NCs additionally possessed photoacoustic and X-ray contrast imaging abilities that could serve in image-guided therapeutic studies.engThis work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material.Journal articlehttp://dx.doi.org/10.1038/srep35961