2021-03-022021-03-022020-12-01San, Ka-yiu, Zhang, Xian, Wu, Hui and Wang, Dan, "KAS-III free FA synthesis." Patent US10851393B2. issued 2020-12-01. Retrieved from <a href="https://hdl.handle.net/1911/110124">https://hdl.handle.net/1911/110124</a>.https://hdl.handle.net/1911/110124The present disclosure describes a genetically engineered a KASIII-independent fatty acid biosynthetic pathway that makes use of the promiscuous nature of the rest of the FAS enzymes (3-ketoacyl-ACP synthetase, 3-ketoacyl-ACP reductase, 3-hydroxyacyl ACP dehydrase, enoyl-ACP reductase) to bypass the KASIII step by providing a Co-A precursor of two or higher than two carbons (such as the four carbon butyryl-CoA) as the starting molecule. Since many CoA-based starter molecules can be supplied for the fatty acid synthesis, much more diversified products can be obtained with various carbon-chain lengths. As such, this disclosure will serve as a powerful and efficient platform to produce low to medium chain length products carrying many different functional groups.37engUtility patentUS10851393B2