2023-03-022023-03-022023-02-21Nicolaou, Kyriacos C., Rhoades, Derek, Kumar, Soundarapandian M., Pattanayak, Manas R. and Lamani, Manjunath, "Derivatives of thailanstatin A, methods of treatment and methods of synthesis thereof." Patent US11584754B2. issued 2023-02-21. Retrieved from <a href="https://hdl.handle.net/1911/114485">https://hdl.handle.net/1911/114485</a>.https://hdl.handle.net/1911/114485In one aspect, the present disclosure provides analogs of thailanstatin of the formula wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein.95engUtility patentUS11584754B2