2017-02-062017-02-062017-01-03Mikos, Antonios G., Wong, Mark E., Young, Simon W., Kretlow, James D., Shi, Meng, Kasper, Kurtis F. and Spicer, Patrick, "Combined space maintenance and bone regeneration system for the reconstruction of large osseous defects." Patent US9532875B2. issued 2017-01-03. Retrieved from <a href="https://hdl.handle.net/1911/93852">https://hdl.handle.net/1911/93852</a>.https://hdl.handle.net/1911/93852Systems, methods and compositions useful for treatment of traumatic bone injuries are provided. In one embodiment, a bone reconstruction system comprising a space maintaining composition comprising porous polymethylmethacrylate; and an osseous generating construct comprising a polymethylmethacrylate chamber that comprises one or more osseous generating materials is provided. Associated compositions and methods are also provided.37engUtility patentUS9532875B2