Direct capture and sequencing reveal ultra-short single-stranded DNA in biofluids

Cheng, Lauren Y.Dai, PengWu, Lucia R.Patel, Abhijit A.Zhang, David Yu2022-10-282022-10-282022Cheng, Lauren Y., Dai, Peng, Wu, Lucia R., et al.. "Direct capture and sequencing reveal ultra-short single-stranded DNA in biofluids." <i>iScience,</i> 25, no. 10 (2022) Cell Press: https://doi.org/10.1016/j.isci.2022.105046.https://hdl.handle.net/1911/113755resulting fluorescence images and compared with tissue histopathology maps. The EGFﾖAlexa 647 signal correlated well with EGFR expression as indicated by immunohistochemistry. A classification algorithm for presence of neoplasia based on the signal from both contrast agents resulted in an area under the curve of 0.83. RegionsengThis is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).Direct capture and sequencing reveal ultra-short single-stranded DNA in biofluidsJournal article1-s2-0-S2589004222013189-mainhttps://doi.org/10.1016/j.isci.2022.105046