Gomel, Madeleine A.Lee, RomiGrande-Allen, K. Jane2019-12-062019-12-062019Gomel, Madeleine A., Lee, Romi and Grande-Allen, K. Jane. "Comparing the Role of Mechanical Forces in Vascular and Valvular Calcification Progression." <i>Frontiers in Cardiovascular Medicine,</i> (2019) Frontiers: https://doi.org/10.3389/fcvm.2018.00197.https://hdl.handle.net/1911/107798regulator of lysosomal function, or by inducing TFEB activation chemically. Because of its small format, rapidity, sensitivity and reproducibility, the NAG one-step cell assay is suitable for multiple procedures, including the high-throughput screening of chemical libraries to identify modulators of NAG expression, folding and activity, and the investigation of candidate molecules and constructs for applications in enzyme replacement therapy, gene therapy, and combination therapies.engThis is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.Journal articlefcvm-05-00197https://doi.org/10.3389/fcvm.2018.00197