Merritt, MichaelZhang, YinLiu, HelenMohan, Radhe2018-06-182018-06-182002-12Merritt, Michael, Zhang, Yin, Liu, Helen, et al.. "A Successive Linear Programming Approach to IMRT Optimization Problem." (2002) <a href="https://hdl.handle.net/1911/101995">https://hdl.handle.net/1911/101995</a>.https://hdl.handle.net/1911/101995We propose to solve the IMRT optimization problem through a successive linear programming approach. Taking advantage of the sensitivity information in linear programming and the re-optimization ability of simplex methods, the proposed approach provides an affordable methodology to efficiently solve problems with dose-volume constraints. Preliminary computational results indicate that, compared to the standard weighted least squares approach, the new approach leads to higher tumor dosage escalation and better conformation.23 ppengTechnical reportTR02-16