Gao, Simon S.Raphael, Patrick D.Wang, RosaliePark, JesungXia, AnpingApplegate, Brian E.Oghalai, John S.2013-04-292013-04-292013Gao, Simon S., Raphael, Patrick D., Wang, Rosalie, et al.. "In vivo vibrometry inside the apex of the mouse cochlea using spectral domain optical coherence tomography." <i>Journal of Biomedical Optics Express,</i> 4, no. 2 (2013) Optical Society of America: http://dx.doi.org/10.1364/BOE.4.000230.https://hdl.handle.net/1911/71011Sound transduction within the auditory portion of the inner ear, the cochlea, is a complex nonlinear process. The study of cochlear mechanics in large rodents has provided important insights into cochlear function. However, technological and experimental limitations have restricted studies in mice due to their smaller cochlea. These challenges are important to overcome because of the wide variety of transgenic mouse strains with hearing loss mutations that are available for study. To accomplish this goal, we used spectral domain optical coherence tomography to visualize and measure sound-induced vibrations of intracochlear tissues. We present, to our knowledge, the first vibration measurements from the apex of an unopened mouse cochlea.engArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.Journal articlehttp://dx.doi.org/10.1364/BOE.4.000230