Bartel, BonnieFarmer, Lisa M.Rinaldi, Mauro A.Young, Pierce G.Danan, Charles H.Burkhart, Sarah E.2018-07-102018-07-102014Bartel, Bonnie, Farmer, Lisa M., Rinaldi, Mauro A., et al.. "Mutation of the Arabidopsis LON2 peroxisomal protease enhances pexophagy." <i>Autophagy,</i> 10, no. 3 (2014) Landes Bioscience: 518-519. https://doi.org/10.4161/auto.27565.https://hdl.handle.net/1911/102363Peroxisomes are critical organelles housing various, often oxidative, reactions. Pexophagy, the process by which peroxisomes are selectively targeted for destruction via autophagy, is characterized in yeast and mammals but had not been reported in plants. In this article, we describe how the peroxisome-related aberrations of a mutant defective in the LON2 peroxisomal protease are suppressed when autophagy is prevented by mutating any of several key autophagy-related (ATG) genes. Our results reveal that plant peroxisomes can be degraded by selective autophagy and suggest that pexophagy is accelerated when the LON2 protease is disabled.engArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.Mutation of the Arabidopsis LON2 peroxisomal protease enhances pexophagyJournal articleArabidopsis thalianaautophagyperoxisome remodelingperoxisomal proteasepexophagyauto-10-518https://doi.org/10.4161/auto.27565