2015-05-042015-05-042014-04-29San, Ka-Yiu, Bennett, George N. and Wang, Yipeng, "Native NAD-dependent GAPDH replaced with NADP-dependent GAPDH plus NADK." Patent US8709753B2. issued 2014-04-29. Retrieved from https://hdl.handle.net/1911/80155.https://hdl.handle.net/1911/80155This invention is metabolically engineer bacterial strains that provide increased intracellular NADPH availability for the purpose of increasing the yield and productivity of NADPH-dependent compounds. In the invention, native NAD-dependent GAPDH is replaced with NADP-dependent GAPDH plus overexpressed NADK. Uses for the bacteria are also provided.9 ppengUtility patentUS8709753B2