Fukuyama, Tohru2009-06-032009-06-031994Li, Tangqing. "Synthetic studies towards the total synthesis of discorhabdin C." (1994) Diss., Rice University. <a href="https://hdl.handle.net/1911/16751">https://hdl.handle.net/1911/16751</a>.https://hdl.handle.net/1911/16751Two synthetic approaches towards the total synthesis of discorhabdin C (3) are described. The general strategy for construction of azacarbocyclic spiro dienone system is to employ an intramolecular para-phenolic alkylation (58 to 43). The key reaction for the first approach is a newly improved aromatic Claisen rearrangement. The key reaction for the second approach is a novel tin-mediated indole synthesis developed in our laboratory.(DIAGRAM, TABLE OR GRAPHIC OMITTED...PLEASE SEE DAI)168 p.application/pdfengCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.Organic chemistryBiochemistryThesisTHESIS CHEM. 1994 LI