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Spanos, Pol D. Kelm, Lea Nicole 2009-06-04T06:45:17Z 2009-06-04T06:45:17Z 2002 Kelm, Lea Nicole. "Hysteretic response of articular cartilage to cyclic loading." (2002) Master’s Thesis, Rice University. <a href="https://hdl.handle.net/1911/17515">https://hdl.handle.net/1911/17515</a>. https://hdl.handle.net/1911/17515 THESIS M.E. 2002 KELM This research investigates the phenomenon of hysteresis in cartilage experimentally. The presence of a hysteresis loop in cartilage indicates energy loss, thereby signaling degradation of cartilage leading to osteoarthritis. Although hysteresis in ligaments and tendons has been studied to a great extent, limited work has been done with regards to cartilage response. In the course of this investigation, tensile tests were performed on rectangular bovine cartilage specimens in one orientation. The testing procedure was based upon published ASTM procedures, modified to account for the size of the specimen. The acquired data were analyzed to determine the energy loss per cycle and the implications that result from the energy loss. These findings can lead to the development of a hysteretic model for cartilage, which may be used in a clinical setting to establish a novel method for determining the state of disease of cartilage. 75 p. application/pdf eng Copyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder. Biomedical engineering Mechanical engineering Hysteretic response of articular cartilage to cyclic loading Thesis Text Mechanical Engineering Engineering Rice University Masters Master of Science open.access