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SACHLEBEN, RICHARD ALAN 2007-05-09T19:39:41Z 2007-05-09T19:39:41Z 1985 SACHLEBEN, RICHARD ALAN. "SYNTHETIC STUDIES ON THE SAFRAMYCINS A, B AND S: A TOTAL SYNTHESIS OF SAFRAMYCIN B." (1985) Diss., Rice University. <a href="https://hdl.handle.net/1911/15930">https://hdl.handle.net/1911/15930</a>. https://hdl.handle.net/1911/15930 Thesis Chem. 1985 Sachleben The Saframycins are naturally occurring antibiotics with an interesting bisquinone structure. The first and only synthesis of saframycin B is described herein. The interesting aspects of this synthesis are the convergent approach and the method of stereochemical control. Studies directed towards adapting the saframycin B synthesis to the synthesis of saframycins A and S are also described. These studies have resulted in the synthesis of a compound structurally related to the saframycins but so far unreported in the literature. (DIAGRAM, TABLE OR GRAPHIC OMITTED...PLEASE SEE DAI) application/pdf eng Copyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder. Organic chemistry SYNTHETIC STUDIES ON THE SAFRAMYCINS A, B AND S: A TOTAL SYNTHESIS OF SAFRAMYCIN B Thesis Text Chemistry Natural Sciences Rice University Doctoral Doctor of Philosophy open.access