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Grande-Allen, K. Jane Mehta, Shail M 2019-05-17T18:57:16Z 2019-05-17T18:57:16Z 2019-05 2019-04-19 May 2019 2019-05-17T18:57:16Z Mehta, Shail M. "Fabrication of a Low-Cost, Motorized, 3D-Printed Mechanical Testing Device Compatible with Confocal Microscopy." (2019) Master’s Thesis, Rice University. <a href="https://hdl.handle.net/1911/105973">https://hdl.handle.net/1911/105973</a>. https://hdl.handle.net/1911/105973 Current mechanical testing approaches in bioengineering involve systems that are bulky, expensive, and unable to work in tandem with many characterization procedures. In this thesis, we report the fabrication of a 3D-printed mechanical testing device with motorized translation controllable over a Bluetooth connection. Furthermore, with a form factor constrained to a 96-well plate, the device is able to fit into most conventional microscopy stages for simultaneous characterization of microstructure deformation under a quantifiable mechanical load. The construction of this device is performed using commercially-available 3D printers and metal fasteners, therefore production costs are as low as $100. Two design approaches to the device are detailed, and results of mechanical testing on multiple synthetic materials, as well as biological tissue, are discussed. We determined that this device, though not yet generalizable to mechanical analysis of all complex materials, does show significant promise as a viable microscopy-compatible mechanical testing device. application/pdf eng Copyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder. Mechanical Testing Microscopy Biomechanics 3D Printing Fabrication of a Low-Cost, Motorized, 3D-Printed Mechanical Testing Device Compatible with Confocal Microscopy Thesis Text Applied Physics Natural Sciences Rice University Masters Master of Science Applied Physics/Bioengineering open.access